L-无花果酶(人)ELISA试剂盒                                             货号：E-HK336

L-ficolin, Human, ELISA kit

背景资料：The human L-ficolin ELISA is a ready-to-use solid-phase enzyme-linked immunosorbent assay based on the sandwich principle with a working time of 3·5 hours· The efficient format of 2 plates with twelve disposable 8-well strips allows free choice of batch size for the assay· Samples and standards are captured by a solid bound specific antibody· Biotinylated tracer antibody will bind to captured L-ficolin· Streptavidin-peroxidase conjugate will bind to the biotinylated tracer antibody· Streptavidin-peroxidase conjugate will react with the substrate, tetramethylbenzidine (TMB)· The enzyme reaction is stopped by the addition of citric acid· The absorbance at 450 nm is measured with a spectrophotometer· A standard curve is obtained by plotting the absorbance (linear) versus the corresponding concentrations of the L-ficolin standards (log)· The human L-ficolin concentration of samples, which are run concurrently with the standards, can be determined from the standard curve··

产品描述：Ficolins are a group of proteins containing both a collagen-like domain and a fibrinogen-like domain· Three forms of ficolins have been identified in humans: L-ficolin, M-ficolin and H-ficolin· L-ficolin is produced primarily by the liver· Whereas H-ficolin is produced by the liver and the lung and M-Ficolin by monocytes, leukocytes and lung cells· L-ficolin recognizes distinct danger-associated molecular patterns (DAMPs) like GlcNAc-structures in Lipoteichoic Acid (LTA) and fungal 1,3 1,3-β-D-glucan· L-ficolin also recognizes N-acetylated compounds such as acetylcholine· Furthermore, L-ficolin recognizes apoptotic cells and participates in the removal of host cells· L-ficolin circulates in complex with MASP-2 and can activate the lectin complement pathway· L-ficolin serum levels are reported with varying concentrations· Polymorphisms in the promoter of the FCN2 gene from which L-ficolin is derived are associated with variation in L-ficolin serum levels· These polymorphisms may influence the affinity of L-ficolin to GlcNAc-structures· L-ficolin deficiencies have not been reported, but low L-ficolin serum levels have been associated with recurrent respiratory infections in children· Interestingly, L-ficolin has been implicated in the unique immune challenge during pregnancy· In maternal plasma of normal pregnancies, a 4- to 5-fold increase in L-ficolin was detected compared to healthy non-pregnant persons· However, significantly lower L-ficolin maternal plasma concentrations were associated with pre-eclamptic pregnancies· Therefore, assessment of L-ficolin is warranted to study its regulatory role in the innate immune system· Normal human plasma contains a L-ficolin concentration ranging from 1 to 14 ug/ml··

产品特点：Detection level 16 ng/ml

保存建议：推荐4℃保存，有效期一年。

定购信息： 

产品名称	规格	操作手册	货号	询价
L-无花果酶(人)ELISA试剂盒	1 x 96 det	PDF	E-HK336-01
L-无花果酶(人)ELISA试剂盒	2 x 96 det	PDF	E-HK336-02
VisionBlue快速细胞活力分析试剂盒	500 次	PDF	C-K303-500

表观遗传学产品全面解决方案列下：

产品名称	规格	操作手册	货号	询价
DNA羟甲基化定量试剂盒(荧光法)	48 次	PDF	A-P-1037-48
DNA羟甲基化定量试剂盒(荧光法)	96 次	PDF	A-P-1037-96
DNA羟甲基化定量试剂盒(比色法)	48 次	PDF	A-P-1036-48
DNA羟甲基化定量试剂盒(比色法)	96 次	PDF	A-P-1036-96
DNA甲基化定量试剂盒(荧光法)	48 次	PDF	A-P-1035-48
DNA甲基化定量试剂盒(荧光法)	96 次	PDF	A-P-1035-96
DNA甲基化定量试剂盒(比色法)	48 次	PDF	A-P-1034-48
DNA甲基化定量试剂盒(比色法)	96 次	PDF	A-P-1034-96
通用DNA甲基化试剂盒(定性分析)	48 次	PDF	A-P-1011-48
通用DNA甲基化试剂盒(定性分析)	96 次	PDF	A-P-1011-96
超敏DNA甲基化定量试剂盒	48 次	PDF	A-P-1021-48
超敏DNA甲基化定量试剂盒	96 次	PDF	A-P-1021-96
总DNA甲基化定量试剂盒	48 次	PDF	A-P-1014-48
总DNA甲基化定量试剂盒	96 次	PDF	A-P-1014-96

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