Anti-N6-methyladenosine (m6A) Antibody（m6A抗体） 货号：E-ABE572
Anti-N6-methyladenosine (m6A) Antibody
Background
N6-methyladenosine (m6A), or methylation of the N6 position of adenosine is a posttranscriptional modification of RNA. Due to a lack of analytical methods, N6-methyladenosine is poorly understood, but new evidence suggests that it is a very common base modification and important physiological regulator. N6-methyladenosine is markedly increased throughout brain development, and is enriched near stop codons, microRNA-binding sites and UTRs, which indicates a fundamental role in the regulation of gene expression. N6-methyladenosine is also highly conserved between human and mouse.
Concentration
100ug,Please refer to the Certificate of Analysis for the lot-specific concentration
Description
1 µg or 2 µg of either negative control DNA oligomers (Lane 1) or N6-methyladenosine DNA oligomers (Lane 2) were probed with Cat. No. ABE571; Anti-N6-methyladenosine (1 µg/mL). Proteins were visualized using a Donkey Anti-Rabbit IgG secondary antibody conjugated to HRP and a chemiluminescence detection system.
Specificity
All ,Expected to react with all species
Isotype
Polyclonal Antibody
Formulation
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.
Storage
Stable for 1 year at 2-8°C from date of receipt.
Purity
Protein A purified
Handling Recommendations
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals
Application
Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory detected N6-methyladenosine in RNA containing N6-methyladenosine (Dominissini, D., et al. (2012). Nature. 485(7397):201-206.; Meyer, K. D., et al. (2012). Cell. 149(7):1635-1646.).
(RNA) Immunoprecipitation Analysis: A representative lot from an independent laboratory detected N6-methyladenosine in methylated RNA containing N6-methyladenosine (Meyer, K. D., et al. (2012). Cell. 149(7):1635-1646.).
Dot Blot Analysis: A representative lot from an independent laboratory detected N6-methyladenosine in a panel of modified oligonucleotides (Meyer, K. D., et al. (2012). Cell. 149(7):1635-1646.; Jia, G., et al. (2011). Nat Chem Biol. 7(12):885-887.).
定购信息：
| 产品名称 |
规格 |
操作手册 |
货号 |
询价 |
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100ug |
PDF |
E-ABE572 |
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