白蛋白蓝色荧光分析试剂盒 货号：E-15002
Albumin Blue Fluorescent Assay Kit
背景资料：The Albumin Blue Fluorescent Assay Kit is a quantitative assay designed to measure albumin levels in biological samples including serum and urine. The kit combines unmatched sensitivity, high specificity and a quick, easy protocol to provide an effective assay for studying albumin.
产品描述：Albumin, produced only in the liver, is the major plasma protein circulating in the bloodstream. It plays a significant role in the maintenance of colloid osmotic pressure and the binding of long-chain fatty acids, bile acids, bilirubin, haematin, calcium and magnesium. It also acts as a carrier for nutritional factors and drugs. Because serum albumin is a reliable prognostic indicator for morbidity and mortality, liver disease, kidney disease and malnutrition, efficient study methods are in high demand. The Albumin Blue Fluorescent Assay Kit provides a simple tool for highly selective and sensitive albumin detection and comes complete with everything required for performing the assay.
产品使用：Sirt1 activator. It suppressed TNFα release from THP-1 cells and stimulated adipogenesis in 3T3L1 cells (ref 1). SIRT1 stimulation by SirtAct leads to decreased tissue factor mediated thrombogenicity in mice (ref 2). It inhibited NFκB activation and reduced inflammatory cytokine production in lamina propria mononuclear cells from IBD patients (ref 3). It prevented and cured experimental Colitis in a mouse model (ref 3).
产品应用：.
Currently, assays that are suitable for determining low concentrations of albumin (< 100 mg/L) are nonspecific, and merely quantify total protein content. In contrast, the Albumin Assay Kit is sensitive, easy to use and specific for albumin. Simply add the Diluent Buffer and Dye Reagent to the standards and samples, then read the fluorescence. The intensity of the fluorescent signal is directly proportional to the albumin concentration of the sample. And, as albumin-bound dye has a greatly increased excitation, the background caused by the emission of any free dye is minimal (Figure 1).
文献参考：
“Albumin blue 580 fluorescence assay for albumin” by Kessler et al (1997) Analytical Biochemistry 248(1):180-182.
“Microalbuminuria and borderline-increased albumin excretion determined with a centrifugal analyzer and the Albumin Blue 580 fluorescent assay” by Kessler et al (1997) Clinical Chemistry 43(6):996-1002.
“Mesangial cell-derived factors alter monocyte activation and function through inflammatory pathways: possible pathogenic role in diabetic nephropathy” by Min et al (2009) Am. J. Physiol. Renal. Physiol. 297:F1229-F1237.
“Hydrophobic nanoparticles improve permeability of cell-encapsulating poly (ethylene glycol)hydrogels while maintaining patternability” by Lee et al (2010) PNAS 107(48):20709-20714.
“Hepatocyte growth factor gene therapy enhances infoltration of macrophages and may induce kidney repair in db/db mice as a model of diabetes” by Flaquer et al (2012) Diabetologia 55:2059-2068.
定购信息：
表观遗传学产品全面解决方案列下：
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