人绒癌-3细胞核提取物 货号：E-36012
JEG-3 nuclear extract
背景资料：JEG-3 nuclear extract was prepared from cell cultures of the JEG-3 human placental choriocarcinoma cell line. These cells are epithelial in morphology and are derived from propagated extravillous trophoblast (EVT) cells of the placenta. EVT cells are a subpopulation of specialized and highly invasive cells. In response to a TGF-β signal secreted from the uterus, these cells are prompted to grow out from the placenta and invade the decidual lining of the uterus. Once they penetrate the decidua, they serve to both anchor the placenta to the uterus and establish an adequate blood supply exchange from the mother to the developing fetus. In research, JEG-3 cells commonly serve as trophoblastic model systems to study mechanisms regulating mammalian reproduction and fetal development. In addition, due to their invasive properties, these cells are also useful in dissecting the underlying processes governing proliferation, migration and invasiveness related to malignant cell behavior.
产品描述：
JEG-3 nuclear extract is specifically recommended for use in studies related to the mechanisms governing 1) proliferation, 2) migration, and 3) invasiveness during mammalian reproduction, fetal development and cancer.
产品应用：
JEG-3 nuclear extract is supplied in Dilution Buffer (20 mM Hepes (pH 7.9), 100 mM KCl, 1 mM MgCl2, 20% glycerol, 0.5 mM PMSF and 0.5 mM DTT).
产品使用：
Extracts have been quality control tested by Western blot and the Electrophoretic Mobility Shift Assay (EMSA).
温度保存：
Lyophilized proteins can be stored at -20°C or -80°C, preferably desiccated. Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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