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| 精彩产品>免疫生物学...E... |
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HL-60细胞核提取物 货号：E-36072
HL-60 nuclear extract
背景资料：HL-60 nuclear extract was prepared from a cell culture of the human promyelocytic leukemia HL-60 cell line. The HL-60 cell line was originally derived from tumor tissue obtained from a 36 year old female patient with acute promyelocytic leukemia. HL-60 cells are primarily neutrophilic myelocyte precursors in morphology and can be induced to differentiate into granulocytic, monocytic, macrophage-like and eosinophil phenotypes depending on the compound treatment. These cells require insulin and transferrin for growth. In research, HL-60 cells are most commonly used to study myeloid differentiation, hematopoiesis, and acute promyelocytic leukemia. Historically, this cell line was used as a model system to study the effect of DNA topoisomerase IIα and IIβ on differentiation and apoptosis of cells.
产品描述：
HL-60 nuclear extract is recommended for use in studies related to 1) myeloid differentiation, 2) hematopoiesis, and 3) acute promyelocytic leukemia.
产品应用：
HL-60 nuclear extract is supplied in Dilution Buffer (20 mM Hepes (pH 7.9), 100 mM KCl, 1 mM MgCl2, 20% glycerol, 0.5 mM PMSF and 0.5 mM DTT).
产品使用：
Extracts have been quality control tested by Western blot and the Electrophoretic Mobility Shift Assay (EMSA).
温度保存：
Lyophilized proteins can be stored at -20°C or -80°C, preferably desiccated. Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
定购信息：
表观遗传学产品全面解决方案列下：
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