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精彩产品>免疫生物学...E... |
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前列腺癌细胞核提取物 (Clone FGC) (E-36051) |
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前列腺癌细胞核提取物 (Clone FGC) 货号:E-36051
LNCaP nuclear extract (Clone FGC)
背景资料:LNCaP nuclear extract (Clone FGC) was prepared from cell cultures of the human prostate adenocarcinoma LNCaP-FGC cell line. The LNCaP-FGC cell line is a subclone of the fibroblast-like LNCaP parental cell line that was originally derived from a supraclavicular lymph node metastatic lesion of a 50 year old Caucasian male patient with metastatic prostate carcinoma. Prostate cancer is the second most common neoplasia in men. Because it is a hormone-responsive cancer, its treatment at initial stages of development typically involves anti-androgen adjuvant therapy. The LNCaP-FGC subclone retains all the properties of the parental LNCaP cell line, including its malignant characteristics, such as the expression of high levels of acid phosphatase, androgen receptors and Prostate Specific Antigen (PSA), and hormone sensitivity. This cell line is most commonly used in research as a model for human prostate cancer.
产品描述:
LNCaP nuclear extract (Clone FGC) is specifically recommended for studies related to prostate cancer.
产品应用:
LNCaP nuclear extract (Clone FGC) is supplied in Dilution Buffer (20 mM Hepes (pH 7.9), 100 mM KCl, 1 mM MgCl2, 20% glycerol, 0.5 mM PMSF and 0.5 mM DTT).
产品使用:
Extracts have been quality control tested by Western blot and the Electrophoretic Mobility Shift Assay (EMSA).
温度保存:
Lyophilized proteins can be stored at -20°C or -80°C, preferably desiccated. Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
定购信息:
表观遗传学产品全面解决方案列下:
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5-hmC是近年来在动物组织中发现的,由胞嘧啶修饰而来。5-hmC在表观遗传学上的功能可能与5-甲基化胞嘧啶(5-mC)不同。尽管到现在为止还不确知其功能,有研究者猜测它在调控基因的表达与关闭过程中起着重要的作用。5-mC的发现让我们不得不重新评估DNA甲基信息,也不得不监测人类的健康组织和病理组织之间5-mC相对分布的差异。在EPI公司的MethylFlash技术之前,我们还没有发现任何直接的常规方法来检测5- hmC,以及区分5-hmC和5-mC
5-hmC 和 5-mC的区别
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