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Human CellExp R-Spondin 3 /RSPO3 (22-146), human recombinant |
中文名称 |
【R Spondin 3】人源细胞表达的重组人R-Spondin 3/RSPO3 (22-146)(10 ug) |
供应商 |
BioVision |
产品货号 |
7463-10 |
产品报价 |
客服1: 客服2: |
购买方式
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银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系010-52406250. |
产品新闻 |
微信号:AD-Bio |
订阅号: Bio-888 |
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背景资料 |
R-Spondin 3 (RSPO3), also called cysteine-rich and single thrombospondin domain containing-1 (CRISTIN1), Protein with TSP type-1 repeat (PWTSR), is a member of the R-Spondin protein family. R-spondins (RSPO) are a recently discovered secretory protein family with four members in human and mouse. Although all four RSPO proteins activate the canonical Wnt pathway, RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. RSPO-3 is expressed ubiquitously and expressed at higher level in placenta, small intestine, fetal thymus and lymph node. RSPO3 is the activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. RSPO3 acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway, probably by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. RSPO3 also acts as a ligand for frizzled FZD8 and LRP6 and may negatively regulate the TGF-beta pathway. |
产品描述 |
该人源细胞表达的重组人R-Spondin 3/RSPO3 (22-146)产品为冻干形式.具体样式见英文说明:Lyophilized from 0.22 um filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization. |
来源宿主 |
提供的【R Spondin 3】人源细胞表达的重组人R-Spondin 3/RSPO3 (22-146)产品的来源为人胚肾HEK293细胞重组表达重组表达. |
序列 |
人源细胞表达的重组人R-Spondin 3/RSPO3 (22-146)蛋白产品,又称RSPO3, CRISTIN1, PWTSR, THS
D2.其对应NCBI基因号为84870,对应Accession号为Q9BXY4.
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溶解建议 |
人源细胞表达的重组人R-Spondin 3/RSPO3 (22-146)产品请按照说明书建议进行溶解操作:Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C. |
保存建议 |
在您收到艾美捷发出的【R Spondin 3】人源细胞表达的重组人R-Spondin 3/RSPO3 (22-146)产品后,建议将其置于-20°C保存. |
产品说明书 |
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