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Human CellExp CD62E/E-Selectin, human recombinant |
中文名称 |
【CD62E】人源细胞表达的重组人CD62E/E-选择素(20ug) |
供应商 |
BioVision |
产品货号 |
7434-20 |
产品报价 |
客服1: 客服2: |
购买方式
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银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系010-52406250. |
产品新闻 |
微信号:AD-Bio |
订阅号: Bio-888 |
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背景资料 |
E-Selectin, also known as CD62 antigen-like family member E (CD62E), endothelial-leukocyte adhesion molecule 1 (ELAM-1), or leukocyte-endothelial cell adhesion molecule 2 (LECAM2), a member of the Selectin family, is a 107-115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1β and TNFα. E selectin has a cassette structure: an N-terminal, C-type lectin domain, an EGF (epidermal-growth-factor)-like domain, 6 Sushi domain (SCR repeat) units, a transmembrane domain (TM) and an intracellular cytoplasmic tail (cyto). During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. The local release of cytokines IL-1 and TNF-α by damaged cells induces the over-expression of E-selectin on endothelial cells of nearby blood vessels. E-selectin mediates the adhesion of tumor cells to endothelial cells, by binding to E-selectin ligands expressed by neutrophils, monocytes, eosinophils, memory-effector T-like lymphocytes, natural killer cells or cancer cells. Furthermore, a number of studies have reported that levels of E-Selectin may be elevated in subjects with a variety of pathological conditions. |
产品描述 |
该人源细胞表达的重组人CD62E/E-选择素产品为冻干形式.具体样式见英文说明:Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization. |
来源宿主 |
提供的【CD62E】人源细胞表达的重组人CD62E/E-选择素产品的来源为人胚肾HEK293细胞重组表达重组表达. |
序列 |
人源细胞表达的重组人CD62E/E-选择素蛋白产品,又称SELE, RP1-117P20.2, CD62E, ELAM1, ESEL, LECAM2, E-Selectin.其对应NCBI基因号为6401,对应Accession号为P16581.
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溶解建议 |
人源细胞表达的重组人CD62E/E-选择素产品请按照说明书建议进行溶解操作:Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C. |
保存建议 |
在您收到艾美捷发出的【CD62E】人源细胞表达的重组人CD62E/E-选择素产品后,建议将其置于-20°C保存. |
产品说明书 |
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