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CCL16, human recombinant |
中文名称 |
【CCL16】重组人趋化因子CCL16(20 ug) |
供应商 |
BioVision |
产品货号 |
4349-20 |
产品报价 |
客服1: 客服2: |
购买方式
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银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系010-52406250. |
产品新闻 |
微信号:AD-Bio |
订阅号: Bio-888 |
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背景资料 |
Human CCL16, is a novel CC chemokine recognized by bioinformatics. NCC-4 cDNA encodes a 120 amino acids along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. HCC4 is vaguely related to other CC chemokines (< 30% homology). Among CC chemokines, CCL-16 has the largest similarity to HCC-1. 2 potential polyadenylation signals are present on the human HCC-4 gene, and as a result, 2 transcripts containing roughly 1,500 base pairs and 500 base pairs have been detected. HCC-4 is expressed weakly by some lymphocytes, including NK cells, T cells, and some T cell clones. The expression of HCC-4 in monocytes is greatly upregulated in the presence of IL-10. CCL16 shows chemotactic activity for lymphocytes and monocytes rather than to neutrophils. NCC-4 has potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. CCL16 demonstrates chemotactic activity for monocytes and thp-1 monocytes, rather than for resting lymphocytes and neutrophils. HCC-4 induces a calcium flux in thp-1 cells that desensitized prior to the expression of rantes. CCL16 Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 97 amino acids and having a molecular mass of 11.2 kDa. The CCL16 is purified by proprietary chromatographic techniques |
产品描述 |
该重组人趋化因子CCL16产品为冻干形式.具体样式见英文说明:Lyophilized from a filtered solution containing 20 mM sodium phosphate buffer, pH 7.4 and 150 mM NaCl. |
来源宿主 |
提供的【CCL16】重组人趋化因子CCL16产品的来源为大肠杆菌重组表达. |
序列 |
重组人趋化因子CCL16蛋白产品,又称C-C motif chemokine 16, Small-inducible cytokine A1
6, IL-10-inducible chemokine, Chemokine LEC, Monotactin-1, Chemokine C
C-4, Lymphocyte and monocyte chemoattractant, CCL-16, HCC-4, HCC4, NCC
4, NCC-4, Liver Expressed Chemokine, LMC, LCC-1, LCC1, MTN-1, MTN1, SC
YL4, ckB12, SCYA16, LEC, ILINCK, MGC117051.其对应NCBI基因号为6360,对应Accession
号为O15467.
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溶解建议 |
重组人趋化因子CCL16产品请按照说明书建议进行溶解操作:Reconstitute in sterile ddH |
保存建议 |
在您收到发出的【CCL16】重组人趋化因子CCL16产品后,建议将其置于-20°C保存. |
产品说明书 |
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