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Epigenetics |
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Epigenetics>【BioVision】 |
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【Serpin E1】重组人Serpin E1/PAI-1(4731-100) |
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Serpin E1/PAI-1, human recombinant |
中文名称 |
【Serpin E1】重组人Serpin E1/PAI-1(100ug) |
供应商 |
BioVision |
产品货号 |
4731-100 |
产品报价 |
客服1: 客服2: |
购买方式
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银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系010-52406250. |
产品新闻 |
微信号:AD-Bio |
订阅号: Bio-888 |
技术微信:hugasis |
销售微:ex-2008 |
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背景资料 |
Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. They are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SERPINE1 and PLANH1, is a secreted protein which belongs to the serpin family. SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Defects in SERPINE1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SERPINE1 defect in the plasma. High concentrations of SERPINE1 have been associated with thrombophilia which is an autosomal dominant disorder in which affected individuals are prone to develop serious spontaneous thrombosis. |
产品描述 |
该重组人Serpin E1/PAI-1产品为冻干形式.具体样式见英文说明:Recombinant Serpin E1/PAI-1 is lyophilized from a 0.2 um filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0. |
来源宿主 |
提供的【Serpin E1】重组人Serpin E1/PAI-1产品的来源为人细胞重组表达. |
序列 |
重组人Serpin E1/PAI-1蛋白产品,又称Plasminogen activator inhibitor 1 (PAI) (PAI-
1) (Endothelial plasminogen activator inhibitor) (Serpin E1).其对应NCBI基因
号为5054,对应Accession号为P05121.
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溶解建议 |
重组人Serpin E1/PAI-1产品请按照说明书建议进行溶解操作:It is recommended to reconstitute the lyophilized Recombinant Human SERPIN E1 in PBS not less than 100ug/ml, which can then be further diluted to other aqueous solutions. |
保存建议 |
在您收到发出的【Serpin E1】重组人Serpin E1/PAI-1产品后,建议将其置于-70°C保存. |
产品说明书 |
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