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Human CellExp Follistatin, human recombinant |
| 中文名称 |
【Follistatin】人源细胞表达的重组人卵泡抑素（10 ug） |
| 供应商 |
BioVision |
产品货号 |
7227-10 |
| 产品报价 |
客服1： 客服2： |
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购买方式
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银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系010-52406250. |
| 产品新闻 |
| 微信号：AD-Bio |
订阅号： Bio-888 |
技术微信:hugasis |
销售微：ex-2008 |
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| 背景资料 |
Follistatin, also known as activin-binding protein, FST and FSH-suppressing protein (FSP), and is a secreted autocrine glycoprotein that is expressed in nearly all tissues of higher animals. Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone. Currently there are three reported isoforms, FS-288, FS-300, and FS-315. Two, FS-288 and FS-315, are known to be created by alternative splicing of the primary mRNA transcript. FS-300 (porcine follistatin) is thought to be the product of posttranslational modification via truncation of the C-terminal domain from the primary amino-acid chain. The activin-binding protein follistatin is produced by folliculostellate (FS) cells of the anterior pituitary. FS cells make numerous contacts with the classical endocrine cells of the anterior pituitary including gonadotrophs. In the tissues activin has a strong role in cellular proliferation. In the blood, activin and follistatin are both known to be involved in the inflammatory response following tissue injury or pathogenic incursion. Follistatin is involved in the development of the embryo. It has inhibitory action on bone morphogenic proteins (BMPs); BMPs induce the ectoderm to become epidermal ectoderm. Inhibition of BMPs allows neuroectoderm to arise from ectoderm, a process which eventually forms the neural plate. Other inhibitors involved in this process are noggin and chordin. Follistatin and BMPs are also known to play a role in folliculogenesis within the ovary. A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy (SMA) in animal models. |
| 产品描述 |
该人源细胞表达的重组人卵泡抑素产品为冻干形式.具体样式见英文说明：Lyophilized from 0.22 um filtered solution in PBS. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization. |
| 来源宿主 |
提供的【Follistatin】人源细胞表达的重组人卵泡抑素产品的来源为人胚胎肾HEK293细胞重组表达重组表达. |
| 序列 |
人源细胞表达的重组人卵泡抑素蛋白产品，又称Follistatin, FS, FST.其对应NCBI基因号为10468，对应Accession
号为P19883.
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| 溶解建议 |
人源细胞表达的重组人卵泡抑素产品请按照说明书建议进行溶解操作：Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C. |
| 保存建议 |
在您收到发出的【Follistatin】人源细胞表达的重组人卵泡抑素产品后，建议将其置于-20°C保存. |
| 产品说明书 |
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