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Thymosin-β4, human recombinant |
| 中文名称 |
【Thymosin β4】重组人胸腺素-β4（10 ug） |
| 供应商 |
BioVision |
产品货号 |
7216-10 |
| 产品报价 |
客服1： 客服2： |
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购买方式
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银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系010-52406250. |
| 产品新闻 |
| 微信号：AD-Bio |
订阅号： Bio-888 |
技术微信:hugasis |
销售微：ex-2008 |
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| 背景资料 |
Thymosin-β4 is a small, actin-sequestering protein belonging to the thymosin-β family that is found at high concentrations within the spleen, thymus, and peritoneal macrophages, where it is most notably responsible for the organization of cytoskeletal structure. In mammalian tissues, this protein acts as a modulator for the polymerization/depolymerization of actin through the formation of a 1:1 complex with the monomer G (globular)-actin, and inhibits actin’s polymerization to form F (filamentous) actin, which together with other proteins binds microfilaments to construct the cytoskeleton. Commonly found at significant quantities within the brain, lungs, liver, kidneys, testes, and heart, Thymosin-β4 has also been shown to be synthesized by cells unrelated to the reticulo-endothelial system, such as myoblasts and fibroblasts, and expressed at irregular levels by several hemopoietic cell lines, malignant lymphoid cells and myeloma cells. In addition to regulating actin polymerization, research has also found Thymosin-β4 to stimulate the secretion of hypothalamic luteinizing hormone-releasing hormone and luteinizing hormone, inhibit the migration of peritoneal macrophages, induce phenotypic changes in T cell lines during early host defense mechanisms, and inhibit the progression of hematopoietic pluripotent stem cells into the s-phase. Recombinant Human Thymosin-β4 is a 5.2 kDa glycoprotein containing 45 amino acid residues. |
| 产品描述 |
该重组人胸腺素-β4产品为冻干形式.具体样式见英文说明：Sterile filtered through a 0.2 micron filter. Lyophilized with no additives |
| 来源宿主 |
提供的【Thymosin β4】重组人胸腺素-β4产品的来源为大肠杆菌重组表达 . |
| 序列 |
重组人胸腺素-β4蛋白产品，又称Tβ-4, Hematopoietic system regulatory peptide, Seraspe
nide, TMSB4X, TB4X, TMSB4.其对应NCBI基因号为7114，对应Accession号为P62328.
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| 溶解建议 |
重组人胸腺素-β4产品请按照说明书建议进行溶解操作：Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C. |
| 保存建议 |
在您收到发出的【Thymosin β4】重组人胸腺素-β4产品后，建议将其置于-20°C保存. |
| 产品说明书 |
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